Cochrane UK Trainees' Journal Club – 9th March

Journal Club #10 – Tuesday 9th March 2021, 19:00-20:00 GMT.

Kinseng Tong

Chair: Kinseng Tong @kinsengt

Kinseng is a Core Surgical Trainee in the Wessex deanery. He graduated from Oxford University in 2018 and completed his foundation training in Cumbria. During his training he has developed an interest in evidence-based medicine and plastic surgery. He has written several publications and presented at international conferences. Through this role he hopes to encourage a wider audience, particularly junior trainees, to incorporate the latest research evidence in their daily practice. 


Antibiotic therapy vs appendectomy for treatment of uncomplicated acute appendicitis - the APPAC randomized clinical trial

Background to the discussion:

Appendectomy has been the mainstay treatment for acute appendicitis. However, a conservative approach with antibiotics alone has also been reported with good success rates. The global Covid-19 pandemic has impacted on surgical practice in many ways, one of which is a return to antibiotic therapy alone in the treatment of uncomplicated acute appendicitis. In this journal club we shall consider the APPAC randomised clinical trial, which compares antibiotic therapy versus appendectomy for the treatment of uncomplicated acute appendicitis. We evaluate this study using the CONSORT checklist. Is this study reliable? What factors affect its internal validity? Is it generalisable? 

Critical appraisal is a key skill, not just for doctors but for all healthcare staff. This journal club is intended for any level of healthcare professional, students and anyone with an interest in evidence-based medicine. We aim to practise a systematic approach to critical appraisal and highlight some of the foundational concepts in randomised controlled trial (RCT) methodology. 

See you at 7pm (GMT) on Tuesday 9th March to discuss this paper.

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